- INNOVA Fermentation Rack
Multi-point Fermentation Monitoring
FEATURES:
- Multipoint monitoring of Oxygen and Carbon Dioxide
- The fast response time makes it possible to sample a large number of fermentors in a short time interval
- The stability of the PAS/MA measuring principle enables long batch-runs without calibration.
- Low sample flow - easy to use with small bench scale fermentors
- Fast and precise response makes it possible to dertermine the respiratory quotient with high integrity
- Inexpensive compared to Mass Spectrometers
BENEFITS:
- Finding optimum age for transfer from seed tank
- Optimize air flow
- Controlling Nutrient addition at optimum rate
- Correlate present run-data to past run-data
The figure above to the right shows a typical fermentation gas monitoring system. The system includes the Fermentation Monitor - INNOVA 1313 and the Multipoint Sampler - INNOVA 1309. Up to three INNOVA 1309's can be used in one system. The bioreactors are operated at slightly over pressure relative to atmospheric. From the exhaust lines a gas sample is drawn from each fermentor and passed through a membrane separator to remove condensed water and possible foam. The sample is then pumped to the multipoint system, the final length of the sample line being NAFION® tubing in order to equalize the water vapour content with the ambient level. Each sample from the fermentors is then passed in turn to the monitor via NAFION® tubing, again at a flow rate of 130 ml/min.
Digram showing a 3-channel monitoring system
Monitoring Lab-scale Fermentations
- The Fermentation Monitor - INNOVA 1313 is equally well suited for monitoring Lab-scale fermentations, due to the very small sample flow required (130 ml/min).
The Fermentation Monitor - INNOVA 1313 is using a very low sample flow (130 ml/min). Depending of the rate of aeration air to the fermentor, this low flow makes it possible to monitor even very small fermentors (down to maybe 500 ml vessels). This way, the same instrument can be used in Labs, in Pilot-plants and up to Production scale, making scaling-up of the process easier.